Publication | Open Access
The<i>Pseudomonas aeruginosa motR</i>gene involved in regulation of bacterial motility
26
Citations
14
References
2000
Year
Gram-negative BacteriologyAntimicrobial Resistance GeneHealth SciencesDrug ResistanceMedicinePathogenesisBacteriologyVirulence FactorMolecular BiologyW51m1 Motility BehaviorMotr GeneMicrobiologyBacterial MotilityMolecular MicrobiologyBacterial PathogensClinical MicrobiologyMicrobial Genetics
A mini-Tn5-Hg insertion mutant derived from Pseudomonas aeruginosa W51D (W51M1) was isolated in which mini-Tn5 insertion disrupted the motR gene showing that it forms part of the cluster involved in bacterial motility and chemotaxis. Characterization of the W51M1 motility behavior, and also of a PAO1 motR::mini-Tn5-Hg mutant, suggests that the product of the motR gene is a negative regulator of bacterial motility which controls the number of flagella per cell.
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