PHARMACOLOGICAL STUDIES ON HEMLOCK WATER DROPWORT

H. F. Grundy, F. Howarth

British Journal of Pharmacology and Chemotherapy · 1956 · 22 citations · 2 references

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Abstract

The Umbellifer, Qenanthe crocata, is found in damp situations in many parts of the British Isles and Western Europe, and is held to be one of our most poisonous indigenous plants. Confusion in nomenclature renders many early reports unreliable, though Vaughan (1722) appears to have recognized the effects produced in man by ingestion of the tubers. Bloc (1873), Demoor (1896, 1897) and Witthaus (1911) report 124, 218, and 159 cases of poisoning respectively, with death rates of between 26 and 44%. In Demoor's series, the mortality among those who suffered convulsions was approximately 70%. Fatal instances of poisoning still appear in the contemporary literature (Lancet, 1947).

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