Concepedia

A New Tin-Free Source of Amidyl Radicals

Fabien Gagosz, Cécile Moutrille, Samir Z. Zard

Organic Letters · 2002 · 92 citations · 6 references

DOI

Concepts

Abstract

[reaction: see text] The readily available N-(O-ethyl thiocarbonylsulfanyl)amides are powerful amidyl radical precursors that undergo 5-exo cyclization to give pyrrolidinone derivatives via a radical-chain reaction initiated by a small amount of lauroyl peroxide.

References

6

Free radical cyclizations involving nitrogen

Alex G. Fallis, Irina M. Brinza · Tetrahedron · 1997 · 378 citations

, , +9

Iminyl, amidyl, and carbamyl radicals from O-benzoyl oximes and O-benzoyl hydroxamic acid derivatives

Jean Boivin, Anne‐Claude Callier‐Dublanchet, Béatrice Quiclet‐Sire et al. · Tetrahedron · 1995 · 144 citations

, , +7

Spirolactams by a novel ipso-radical cyclisation and loss of aromaticity

Jean Boivin, Mohammed Yousfi, Samir Z. Zard · Tetrahedron Letters · 1997 · 66 citations

, , +12

A new source of nitrogen centered radicals

Anne‐Claude Callier‐Dublanchet, Biatrice Quiclet-Sire, Samir Z. Zard · Tetrahedron Letters · 1995 · 57 citations

, , +4

A mild new procedure for production, cyclization and trapping of amidyl radicals: application to a formal total synthesis of peduncularine

Xichen Lin, Didier Stien, Steven M. Weinreb · Tetrahedron Letters · 2000 · 49 citations

, , +7