Apparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values used

Abstract

ADC changes of up to 40% were seen with the use of different b-values. Using a lower b-value ≥ 150 s/mm(2) and an upper b-value ≥ 700 s/mm(2) limited the variation to less that 10% from the reference ADC value. By eliminating the contribution of perfusion the uncertainty of quantitative ADC values were significantly reduced.