Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

Irfan A. Asangani, Suhail Ahmed Kabeer Rasheed, Dessislava A. Nikolova et al. · Oncogene · 2007 · 1.9K citations

Medicine, Molecular Biology, Oncology +14

SMAD proteins control DROSHA-mediated microRNA maturation

Brandi N. Davis‐Dusenbery, Aaron C. Hilyard, Giorgio Lagna et al. · Nature · 2008 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

Li‐Xu Yan, Xiu-Fang Huang, Qiong Shao et al. · RNA · 2008 · 1.2K citations · Full text

Medicine, Molecular Biology, Oncology +17

Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells

Lisa B. Frankel, Nanna R. Christoffersen, Morten Lindow et al. · Journal of Biological Chemistry · 2007 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

MicroRNA-21 Targets the Tumor Suppressor Gene Tropomyosin 1 (TPM1)

Shuomin Zhu, Min-Liang Si, Hailong Wu et al. · Journal of Biological Chemistry · 2007 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +16