The common -675 4G/5G polymorphism in the plasminogen activator inhibitor –1 gene is strongly associated with obesity

Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction.

Per Eriksson, Bengt Kallin, Peter Båvenholm et al. · Proceedings of the National Academy of Sciences · 1995 · 744 citations · Full text

Genetics, Genetic Epidemiology, Human Polymorphism +17

The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells

Sally J. Dawson, B. Wiman, Anders Hamsten et al. · Journal of Biological Chemistry · 1993 · 569 citations · Full text

Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals

Per Eriksson, Signy Reynisdottir, Fredrik Lönnqvist et al. · Diabetologia · 1998 · 224 citations · Full text

Obesity, Metabolic Syndrome, Body Composition +15

Disruption of the plasminogen activator inhibitor‐1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice

Katrin Schäfer, Kazuhiku Fujisawa, Stavros Konstantinides et al. · The FASEB Journal · 2001 · 173 citations · Full text

Influence of PAI-1 on Adipose Tissue Growth and Metabolic Parameters in a Murine Model of Diet-Induced Obesity

Pierre‐Emmanuel Morange, H.R. Lijnen, Marie‐Christine Alessi et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2000 · 129 citations