Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox, +49

Nature

Somatic VariantBraf GeneGeneticsCancer GenomicsCancer Genetics +3

MicroRNAs Modulate Hematopoietic Lineage Differentiation

Chang‐Zheng Chen, Ling Li, Harvey F. Lodish, +1

Science

Cell LineageDevelopmental BiologyMedicineGeneticsStem Cells +11

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

Jennifer A. Chan, Anna M. Krichevsky, Kenneth S. Kosik

Cancer Research

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra, +17

Cancer Cell

Tumor BiologyPancreatic CancerMedicineHistopathologyGastroenterology +6

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

Concepción Almoguera, Darryl Shibata, Kathleen Forrester, +3

Cell

Pancreatic CancerMalignant DiseaseMedicinePathologyCancer Genomics +5

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Jeffrey A. Engelman, Liang Chen, Xiaohong Tan, +18

Nature Medicine

Effective UseMek InhibitorsOncologyMedicinePathology +7

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

Shuomin Zhu, Hailong Wu, Fangting Wu, +3

Cell Research

Tumor BiologySmall RnaTumor SuppressorMicrorna DetectionMedicine +2

Activated Kras and <i>Ink4a/Arf</i> deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

Andrew J. Aguirre, Nabeel Bardeesy, Manisha Sinha, +5

Genes & Development

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

Galina Gabriely, Thomas Würdinger, Santosh Kesari, +4

Molecular and Cellular Biology

PathologyCancer BiologyGliomaTumor BiologyMicrorna 21 +14

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

Benjamin Kefas, Jakub Godlewski, Laurey Comeau, +8

Cancer Research

Neuro-oncologySystems BiologyAkt PathwayGliomaCritical Cancer Pathways +13