Peripheral Neuropathy of the Alcoholic: I, Aetiological Role of Aneurin and Other B-complex Vitamins

Abstract

Peripheral neuropathy in alcoholics is usually attributed to a lack of aneurin Demonstration that pantothenic acid The present investi- gation was therefore undertaken to evaluate further the role of aneurin and other B-complex vitamins in the development of this condition. The study consisted of (a) determining circu- lating levels of aneurin, riboflavin, nicotinic acid, pantothenic acid, biotin, pyridoxine, vitamin BI2, and folic acid in alcoholic patients with and without neuropathy; and (b) an evaluation of the responsiveness of patients with neuropathy to various members of the B-complex group.