Effect of non-uniform initial drug concentration distribution on the kinetics of drug release from glassy hydrogel matrices

Conduction of heat in solids

C. J. Tranter · Journal of the Mechanics and Physics of Solids · 1959 · 18.5K citations

Natural Sciences, Materials Science, Physics +10

Mechanism of sustained‐action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices

Tsunehiko Higuchi · Journal of Pharmaceutical Sciences · 1963 · 4.8K citations

Pharmacy, Pharmaceutics, Pharmacology +17

Rate of Release of Medicaments from Ointment Bases Containing Drugs in Suspension

Takeru Higuchi · Journal of Pharmaceutical Sciences · 1961 · 2.2K citations

Pharmacy, Pharmaceutics, Pharmacology +12

Release of Medroxyprogesterone Acetate from a Silicone Polymer

T.J. Roseman, William I. Higuchi · Journal of Pharmaceutical Sciences · 1970 · 287 citations

Pharmacy, Bioengineering, Pharmaceutics +12

Diffusional release of a solute from a polymeric matrix — approximate analytical solutions

Lee P.I. · Journal of Membrane Science · 1980 · 244 citations

Pharmacy, Chemical Engineering, Pharmaceutics +12