Publication | Closed Access
Tuning Reactivity of Glycosyl Imidinium Intermediate for 2-Azido-2-deoxyglycosyl Donors in α-Glycosidic Bond Formation
51
Citations
21
References
2013
Year
α-Glycosidic Bond FormationBioorganic ChemistryEngineeringBiochemistryGlycosylationNatural SciencesModulated Glycosylation ContextGlycobiologyGlycosyl Imidinium Intermediate2-Azido-2-deoxyglycosyl DonorsOrganic ChemistryNucleophile AdditivesCarbohydrate-protein InteractionChemistryEnzymatic ModificationSynthetic ChemistryBiomolecular EngineeringEffective Modulator
The chemical properties of nucleophile additives were investigated in a modulated glycosylation context. N-Formylmorpholine (NFM) was found to be an effective modulator for glycosylation with less reactive 2-azido-2-deoxythioglucosyl and thiogalactosyl donors.
| Year | Citations | |
|---|---|---|
Page 1
Page 1