Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

Armen N. Akopian, Lucia G. Sivilotti, John N. Wood · Nature · 1996 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +14

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel.

Mary Gellens, Alfred L. George, L Q Chen et al. · Proceedings of the National Academy of Sciences · 1992 · 630 citations

Medicine, Cardiology, Pharmacology +17

Expression of functional sodium channels from cloned cDNA

Masaharu Noda, Takayuki Ikeda, Harukazu Suzuki et al. · Nature · 1986 · 536 citations

Life Sciences, Molecular Biology, Physiology +12

Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II

Heinrich Terlau, Stefan H. Heinemann, Walter Stühmer et al. · FEBS Letters · 1991 · 472 citations · Full text

Natural Sciences, Biophysics, Molecular Biology +17

Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoform.

R. B. Rogart, Leanne L. Cribbs, Louis Muglia et al. · Proceedings of the National Academy of Sciences · 1989 · 389 citations · Full text

Medicine, Molecular Biology, Pharmacology +17