Concepedia

Hypoxia-inducible factor-1α correlates with MET and metastasis in node-negative breast cancer

Helen H.W. Chen, Wu‐Chou Su, Pin Wen Lin, How‐Ran Guo, Wen‐Ying Lee

Breast Cancer Research and Treatment · 2006 · 66 citations · 35 references

DOI

Concepts

References

35

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

, , +17

Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer et al. · Molecular and Cellular Biology · 1996 · 4K citations · Full text

, , +15

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

Hua Zhong, Angelo M. De Marzo, Erik Laughner et al. · PubMed · 1999 · 2.2K citations

, , +14

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

Michael Höckel, Karlheinz Schlenger, Bernard Aral et al. · PubMed · 1996 · 1.7K citations

, , +13

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

Jeremy Brown, Amato J. Giaccia · PubMed · 1998 · 1.5K citations

, , +16