New England Journal of Medicine · 1999 · 461 citations · 81 references
MedicineMaternal HealthObstetricsDiabetologyGestational DiabetesMaternal-fetal MedicineDiabetes ManagementDiabetes MellitusGestational Diabetes MellitusMaternal ComplicationsObstetric ManagementPregnancyDiagnosis In Gestational DiabetesMaternal Diabetes ManagementPregnancy Glucose ManagementPregnancy-related Hyperglycemia
Gestational diabetes mellitus is defined as glucose intolerance that is first detected during pregnancy.1 This simple definition belies the complexity of a condition that spans a spectrum of glycemia, pathophysiology, and clinical effects and for which there is a wide diversity of opinion regarding detection and clinical management. There is convincing evidence that mild maternal hyperglycemia is a risk factor for fetal morbidity,2 but that morbidity occurs only in a minority of cases. Failure to recognize and treat the condition will result in unnecessary morbidity in some pregnancies, whereas overly aggressive approaches to detection and treatment will result in unneeded . . .
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