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Enantioselective synthesis of (−)-cytoxazone and (+)-epi-cytoxazone, novel cytokine modulators via Sharpless asymmetric epoxidation and l-proline catalyzed Mannich reaction

BiochemistryNatural SciencesDiversity-oriented SynthesisStereoselective SynthesisNovel Cytokine ModulatorsPharmacologyAsymmetric CatalysisMannich ReactionEnantioselective SynthesisBiomolecular EngineeringSharpless Asymmetric Epoxidation