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Simultaneous determination of phentermine and topiramate in human plasma by liquid chromatography–tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study

Analytical InstrumentationMass SpectrometryPharmacologyPharmacokinetic StudyHuman PlasmaAnalytical ChemistrySimultaneous DeterminationLiquid ChromatographyClinical ChemistryChromatographic AnalysisMedicineChromatographyDrug Analysis