Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti)

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Effects of the <i>obese</i> Gene Product on Body Weight Regulation in <i>ob</i> / <i>ob</i> Mice

Mary Ann Pelleymounter, Mary Jane Cullen, Mary Baker et al. · Science · 1995 · 4K citations

Life Sciences, Biochemistry, Endocrinology +17

Leptin increases uncoupling protein expression and energy expenditure

P. J. Scarpace, Michael E. Matheny, Brad H. Pollock et al. · American Journal of Physiology-Endocrinology and Metabolism · 1997 · 393 citations

Life Sciences, Endocrinology, Physiology +16

Circulating Leptin Levels Are Modulated by Fasting, Cold Exposure and Insulin Administration in Lean but Not Zucker (fa/fa) Rats as Measured by ELISA

Laura J. Hardie, D. Vernon Rayner, Stephen D. Holmes et al. · Biochemical and Biophysical Research Communications · 1996 · 301 citations

Medicine, Endocrinology, Physiology +8

Acute cold-induced suppression of <i>ob</i> (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system

Paul Trayhurn, John S. Duncan, D. Vernon Rayner · Biochemical Journal · 1995 · 292 citations · Full text

Life Sciences, Endocrinology, Physiology +16