Effect of Mitomycin C in Pterygium Surgery on Corneal Endothelium

Abstract

A 5-minute application of MMC 0.02% to the bare sclera during pterygium surgery has an immediate and significant effect on endothelial cell density, which remains stable for up to 90 days. Furthermore, longer-term studies are needed of different concentrations and durations of the drug and of procedures wherein MMC is applied before excision of the pterygium head.