The Decreased Phosphorylation of Cyclic Adenosine Monophosphate (cAMP) Response Element Binding (CREB) Protein in the Central Amygdala Acts as a Molecular Substrate for Anxiety Related to Ethanol Withdrawal in Rats

Abstract

These novel results suggest the possibility that decreased CREB phosphorylation in the central amygdala acts as a common molecular correlate for anxiety and alcohol-drinking behaviors and also is correlated with anxiety related to ethanol withdrawal.