Experimental Studies on the Nervous Control of the Renal Circulation-Effect of the Electrical Stimulation of the Diencephalon on the Renal Circulation

Abstract

An attempt has been made to investigate the changes in blood pressure and renal blood flow induced by electrical stimulation of the diencephalon of dogs and to elucidate the significance of diencephalon in the regulation of renal circulation. The stimulation of the medial and midline nuclei group in the thalamus and most of the hypothalamic and subthalamic nuclei resulted in an increase in the blood pressure and a decrease in the renal blood flow which was attributed to the renal vasoconstriction. The stimulation of a part of the ventral and lateral nuclei group in the thalamus, a part of the preoptic area and anterior and middle portion in the hypothalamus resulted in a fall in blood pressure associated with a decrease in renal blood flow and it was believed that the renal blood vessel induced practically no or very slight constriction. On stimulation of the geniculate bodies, the ventral and lateral nuclei group, there often occurred little or no change in circulatory responses. No obvious findings were obtained in this case which suggested the presence of renal vasodilator nerve in these areas.