Antimicrobials and the Risk of Torsades de Pointes

A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions

Eugène van Puijenbroek, Andrew Bate, Hubert G.M. Leufkens et al. · Pharmacoepidemiology and Drug Safety · 2002 · 1.3K citations

Pharmacy, Pharmacology, Clinical Pharmacology +16

Clinical Evaluation of QT/QTc Prolongation and Proarrhythmic Potential for Nonantiarrhythmic Drugs: The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use E14 Guideline

Börje Darpö, T Nebout, Philip T. Sager · The Journal of Clinical Pharmacology · 2006 · 321 citations

Medicine, Cardiology, Pharmacology +13

Introducing MEDWatch. A new approach to reporting medication and device adverse effects and product problems

David A. Kessler · JAMA · 1993 · 270 citations

Pharmacy, Pharmaceutical Policy, Drug Approval Processes +16

Impact of Safety Alerts on Measures of Disproportionality in Spontaneous Reporting Databases

Fleur Grégoire, Annie Fourrier‐Réglat, Françoise Haramburu et al. · Drug Safety · 2007 · 245 citations

Health Professions, Risk Management, Patient Safety +12

Rates of Torsades de Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin

Richard Frothingham · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · 2001 · 208 citations

Pharmacy, Pharmacology, Pharmacotherapy +5