Die Synthese eines Cephamderivats mittels Vierkomponenten-Kondensation /The Synthesis of a Cepham Derivative by Four Component Condensation

Abstract

Abstract A five-step synthesis of a cepham derivative from a known, a,β,β-trihydroxyisobutyraldehyde derivative (1) and the sodium thioenolate of C-formyl N-phthaloyl methyl glycinate (2) is described. The key step of the synthesis is a four component condensation.