Effect of Repeated Injection and Continuous Infusion of Omeprazole and Ranitidine on Intragastric Ph Over 72 Hours Figure 1

Abstract

Our study shows, for the first time, that omeprazole infusion was significantly superior to all other regimens by having a high median pH >6 on each day. The tolerance effect of ranitidine, however, led to a rapid loss of antisecretory activity on days 2 and 3, rendering it inappropriate for situations in which high intragastric pH-levels appear to be essential.