Injectable Ibuprofen: Preliminary Evaluation of Its Ability to Decrease Peritendinous Adhesions

Abstract

Peritendinous adhesions continue to limit the full return of hand function following flexor tendon injury and repair. Pilot studies in rabbits demonstrated the ability of ibuprofen (Motrin) to reduce intra-abdominal adhesions. In this study, ibuprofen injected at the site of flexor tendon repair significantly reduced the restrictive effects of peritendinous adhesions in primates.