Knoevenagel Condensation of Aldehydes with Meldrum's Acid in Ionic Liquids

Abstract

Abstract The Knoevenagel condensation of Meldrum's acid with aromatic aldehydes proceeded efficiently in the recyclable ionic liquid [bmim]BF4 at room temperature in the presence of catalytic amounts of piperidine. Keywords: Active methylene compoundsionic liquidKnoevenagel condensationMeldrum's acid ACKNOWLEDGMENT This work was supported by an Indiana University–Purdue University Fort Wayne Summer Faculty Research Grant. Notes a All reactions run with 4-methoxybenzaldehyde (2 mmol) and Meldrum's acid (2 mmol) in ionic liquids (1 g) at room temperature for 10 h. b Isolated 3e yields. a At room temperature in [bmim]BF4 in the presence of 10 µL piperidine as the catalyst. b Isolated yields.