Guest Preorganization: An Alternative ���Bioinspired��� Paradigm in Host���Guest Chemistry

Abstract

The ubiquitous tris(pyrazolyl)borate family of ligands can recognize more than metal cations! Host–guest complexes between elaborated tris(pyrazolyl)borate ligands and protonated amines (see picture) and cationic octahedral metal complexes are described. The latter is an example of an alternative bio-inspired paradigm, in which the guest is preorganized to promote recognition, rather than the host. Supporting information for this article is available on the WWW under http://www.angewandte.org or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.