Drug transport to the brain: comparison between in vitro and in vivo models of the blood-brain barrier

Long-term culture of capillary endothelial cells.

Judah Folkman, C C Haudenschild, Bruce R. Zetter · Proceedings of the National Academy of Sciences · 1979 · 778 citations · Full text

Endothelial Cell Pathobiology, Regenerative Medicine, Conditioned Medium +14

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

J Booher, M. Sensenbrenner · PubMed · 1972 · 760 citations

Glial Biology, Brain Development, Neurodevelopment +20

Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard

William H. Oldendorf · Brain Research · 1970 · 546 citations

Radiolabeled Substances, Cerebrospinal Fluid, Radioanalytical Chemistry +10

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

Marie‐Pierre Dehouck, Stéphane Méresse, Pierre Delorme et al. · Journal of Neurochemistry · 1990 · 541 citations

Endothelial Cells, Biomedical Engineering, Cellular Physiology +22

Development of the blood-brain barrier

Werner Risau, Hartwig Wolburg · Trends in Neurosciences · 1990 · 532 citations

Blood–brain Barrier, Neurophysiology, Blood-brain Barrier +10