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Daphnane-Type Diterpene Orthoesters and their Biological Activities
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2002
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BiologyMolecular PharmacologyPolyphenolicsBioorganic ChemistryDaphnane-type Diterpene OrthoestersDaphnane OrthoestersMedicineTumour PromotionNatural SciencesHerbal MedicineVr1 ActivationPhytopharmacologyPhytochemicalPhytochemistryPharmacologyBiomolecular EngineeringDrug DiscoveryOxidative Stress
Daphnane orthoesters are the active ingredients of plant remedies from the Western, Chinese and African traditional medicine, and have provided important tools to investigate medicinally relevant processes like tumour promotion, apoptosis, neurotrophism, and VR1 activation. The occurrence, biological activity, and molecular pharmacology of these compounds will be reviewed.