Cloning and nucleotide sequence of heavy- and light-chain cDNAs from a creatine-kinase-specific monoclonal antibody

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Pharmacy, Biotechnology, Molecular Biology +13

Sequences of proteins of immunological interest

Analytical Biochemistry · 1984 · 3.4K citations

Life Sciences, Immunology, Molecular Biology +10

A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

John F. Kearney, Andreas Radbruch, B Liesegang et al. · The Journal of Immunology · 1979 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Plasmid screening at high colony density

Douglas Hanahan, Matthew Meselson · Gene · 1980 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +10