Gypsum‐Catalyzed One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2<i>(1H)</i> Under Solvent‐Free Conditions

Abstract

In view of the emerging importance of the green chemistry principles in chemical and pharmaceutical industries, we disclose, herein, a new economic approach producing the biologically active dihydropyrimidinones in good yields using the solventless one‐pot Biginelli condensation in the presence of gypsum as an environmental friendly and recycled catalyst.