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Leptin-Replacement Therapy for Lipodystrophy

DOIFull Paper Access

1.2K

Citations

41

References

2002

Year

Elif A Oral, Vinaya Simha, Elaine Ruiz, Alexa Andewelt, Ahalya Premkumar, P. G. Snell, A. Wagner, Alex M. DePaoli, Marc L. Reitman, Simeon I. Taylor,
New England Journal of Medicine

Abstract

Leptin-replacement therapy improved glycemic control and decreased triglyceride levels in patients with lipodystrophy and leptin deficiency. Leptin deficiency contributes to the insulin resistance and other metabolic abnormalities associated with severe lipodystrophy.

References

YearCitations

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