Scientific Reports · 2012 · 94 citations · 21 references
EngineeringBioengineeringBiomedical EngineeringBiomedical ImagingBiomedical OpticsBiophotonicsCellular ImagingFlow CytometryMedical ImagingMedical Imaging InstrumentationOptical ImagingUltrafast OpticsBiological ImagingLaser ScannersOptical ScannersPrecisionRaster ScanningScan Speed
Laser scanning technology is one of the most integral parts of today's scientific research, manufacturing, defense, and biomedicine. In many applications, high-speed scanning capability is essential for scanning a large area in a short time and multi-dimensional sensing of moving objects and dynamical processes with fine temporal resolution. Unfortunately, conventional laser scanners are often too slow, resulting in limited precision and utility. Here we present a new type of laser scanner that offers ∼1,000 times higher scan rates than conventional state-of-the-art scanners. This method employs spatial dispersion of temporally stretched broadband optical pulses onto the target, enabling inertia-free laser scans at unprecedented scan rates of nearly 100 MHz at 800 nm. To show our scanner's broad utility, we use it to demonstrate unique and previously difficult-to-achieve capabilities in imaging, surface vibrometry, and flow cytometry at a record 2D raster scan rate of more than 100 kHz with 27,000 resolvable points.
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Two-Photon Laser Scanning Fluorescence Microscopy
Winfried Denk, James H. Strickler, Watt W. Webb · Science · 1990 · 9.4K citations
Brent Schwarz · Nature Photonics · 2010 · 663 citations
Computing, Geography, Geoinformatics +10
Colour-barcoded magnetic microparticles for multiplexed bioassays
Howon Lee, Junhoi Kim, Hyoki Kim et al. · Nature Materials · 2010 · 399 citations