Does tranexamic acid reduce desmopressin-induced hyperfibrinolysis?

Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: acquired transient platelet dysfunction associated with selective alpha-granule release.

Laurence A. Harker, Thomas W. Malpass, Herman Branson et al. · PubMed · 1980 · 663 citations

Medicine, Hematology, Surgery +17

Treatment with Desmopressin Acetate to Reduce Blood Loss after Cardiac Surgery

E W Salzman, Mark Weinstein, Ronald M. Weintraub et al. · New England Journal of Medicine · 1986 · 512 citations

Medicine, Hematology, Surgery +17

Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: implications for pathophysiology and therapy of von Willebrand's disease subtypes

ZM Ruggeri, PM Mannucci, R Lombardi et al. · Blood · 1982 · 364 citations · Full text

Medicine, Hematology, Pharmacology +14

Prophylactic tranexamic acid decreases bleeding after cardiac operations

Jan C. Horrow, James M. Hlavacek, Michael D. Strong et al. · Journal of Thoracic and Cardiovascular Surgery · 1990 · 258 citations

Medicine, Perioperative Medicine, Surgery +14

Hemostatic effects of tranexamic acid and desmopressin during cardiac surgery.

Jan C. Horrow, Daniel F. Van Riper, Michael D. Strong et al. · Circulation · 1991 · 192 citations

Medicine, Pharmacology, Surgery +17