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The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial growth

Aldehyde DehydrogenaseAlcohol DehydrogenasesBiochemistryPseudomonas AeruginosaN-diethylthiocarbamoyl SulfoneMicrobiologyAntimicrobial CompoundArrest Bacterial Growth