Renal Failure · 2014 · 22 citations · 21 references
MedicineNephrologyOphthalmologyHemodialysisOcular DiseaseRenal Replacement TherapyChronic Kidney DiseaseDry Eye DiseaseDry Eye EvaluationEye ExaminationOcular Surface DiseaseRenal ImpairmentChronic Renal InsufficiencyDry Eye AssessmentDry Eye SymptomatologyMatched Control GroupOphthalmic Clinical ExaminationTear Break-up TimeTear Film DisordersTear Film Imaging
OBJECTIVES: To evaluate dry eye symptoms and clinical tear film alterations in patients with chronic renal failure (CRF). MATERIALS AND METHODS: Thirty-five non-diabetic CRF patients undergoing hemodialysis, and 31 healthy individuals were enrolled. An ocular surface disease index questionnaire (OSDI) was administered, and after a complete ocular examination, Schirmer and tear break-up time (TBUT) tests were performed. RESULTS: OSDI scores were significantly higher (p<0.01) and TBUT tests were significantly lower (p=0.01) in CRF patients than in the control group. Schirmer test results were also lower in the CRF patients group, but lacked statistical significance (p=0.20). CONCLUSION: Patients with CRF should be advised to obtain an ophthalmic examination, especially for dry eye.
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