Publication | Closed Access
Copper-Catalyzed Aerobic Oxidative Amidation of Terminal Alkynes: Efficient Synthesis of Ynamides
470
Citations
9
References
2008
Year
Terminal AlkynesChemical EngineeringCross-coupling ReactionEngineeringCyclic CarbamatesOrganic ChemistryCopper-catalyzed MethodOrganometallic CatalysisCatalysisEfficient SynthesisChemistrySynthesis MethodSynthetic ChemistryCatalytic Synthesis
A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles.
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