Publication | Closed Access
A Search for Associations between Genetical Polymorphic Systems and Physical, Biochemical and Haematological Variables
15
Citations
0
References
1974
Year
HypertensionCardiometabolic RiskGeneticsGenetic EpidemiologyHuman PolymorphismBlood PressureClinical GeneticsPolymoφhic Gene LociGenotype-phenotype AssociationMolecular EcologyBiostatisticsPublic HealthDyslipidemiaYoung PeopleCardiovascular EpidemiologyClinical NutritionHaematological VariablesStatistical GeneticsCardiovascular ReactivityGenetic VariationPopulation GeneticsGenetic BasisGenetical Polymorphic SystemsEpidemiologyBiologyLinkage DisequilibriumGenetic DeterminantCardiovascular DiseaseEvolutionary BiologyMedicineCardiovascular GeneticsPhysical Variables
A total of 811 young people (16–27 years) of both sexes were studied in a health screening program during which multiple biochemical, haematological, and physical variables were measured. In addition, the phenotypes of these subjects were established at 22 polymoφhic gene loci. Analysis of variance by several methods showed no more statistically significant differences than would be expected by chance in any of these variables between persons of distinct phenotypes apart from those associations which have been delineated previously (e.g., cholesterol and ABO blood group, alkaline phosphatase and ABO blood group). More interesting findings were those which related the variables among themselves. Thus, weight, serum protein level, and red blood cell measurements were found to be positively correlated to a substantial extent with blood pressure readings.