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Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1

Neurodegenerative DiseasesMice Double TransgenicAlzheimer's DiseaseMolecular NeuroscienceAlzheimer MutantHuman TauDegenerative PathologyProtein MisfoldingNeuroscienceMolecular NeurobiologyNeurodegenerationMedicineCell BiologySocial Sciences