Target-induced strand release (TISR) from aptamer–DNA duplex: A general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein

Jyun Yoshizumi, Satoshi Kumamoto, Mitsunobu Nakamura, Kazushige Yamana

The Analyst · 2008 · 60 citations · 14 references

Concepts

Abstract

We describe a general strategy for electronic aptamer-based biosensor that is based on target-induced strand release (TISR) of a redox-modified aptamer from the aptamer-capture DNA duplex bound on an electrode.

References

14