5-Bromopentadienal: a versatile intermediate for the synthesis of functionalized polyenic compounds

Abstract

5-Bromopentadienal 1b(n= 2), easily obtained from the potassium glutaconaldehyde salt, is used as precursor of ω-bromoheptatrienal 1d, ω-bromomethoxyhexatriene 2, diene diols 4, diene diones 5, 1,6-dibromohexa-1,3,5-triene 6 and 1,8 triene diol 8, of controlled configuration.