Responsive and mitochondria-specific ruthenium(ii) complex for dual in vitro applications: two-photon (near-infrared) induced imaging and regioselective cell killing

Abstract

A mitochondria-permeable ruthenium(II) complex has been designed as a responsive probe which may be used to sensitize the formation of singlet oxygen (Phi(Delta) = 0.93) and cause local damage in cellulo when exposed to UV and near-infrared laser excitation.