Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes

Oxidative Stress-mediated, Post-translational Loss of MafA Protein as a Contributing Mechanism to Loss of Insulin Gene Expression in Glucotoxic Beta Cells

Jamie S. Harmon, Roland Stein, R. Paul Robertson · Journal of Biological Chemistry · 2005 · 232 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

Impaired Gene and Protein Expression of Exocytotic Soluble <i>N</i>-Ethylmaleimide Attachment Protein Receptor Complex Proteins in Pancreatic Islets of Type 2 Diabetic Patients

Claes‐Göran Östenson, Herbert Y. Gaisano, Laura Sheu et al. · Diabetes · 2006 · 229 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

MAFA controls genes implicated in insulin biosynthesis and secretion

H. Wang, Thierry Brun, Kohsuke Kataoka et al. · Diabetologia · 2006 · 200 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats

C. -G. �stenson, Samy M. Abdel‐Halim, Joanne Rasschaert et al. · Diabetologia · 1993 · 96 citations · Full text

Life Sciences, Biochemistry, Physiology +10

Enzymatic, metabolic and secretory patterns in human islets of Type 2 (non-insulin-dependent) diabetic patients

Josefa Fernández-Álvarez, Ignacio Conget, Joanne Rasschaert et al. · Diabetologia · 1994 · 94 citations

Life Sciences, Endocrinology, Physiology +17