Concepedia

Glucocorticoid therapy suppresses abnormal secretion of big IGF‐II by non‐islet cell tumours inducing hypoglycaemia (NICTH)

J D Teale, V. Marks

Clinical Endocrinology · 1998 · 105 citations · 16 references

DOI

Abstract

Glucocorticoid therapy has been demonstrated to consistently reverse the biochemical abnormalities caused by tumour-derived big IGF-II compared with the potentially adverse stimulatory effects of hGH treatment in causing increases in serum levels of big IGF-II.

References

16

Synthesis and Secretion of Insulin-like Growth Factor II by a Leiomyosarcoma with Associated Hypoglycemia

William H. Daughaday, Mary Ann Emanuele, Marion H. Brooks et al. · New England Journal of Medicine · 1988 · 350 citations

Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects.

H P Guler, Christoph Schmid, J. Zapf et al. · Proceedings of the National Academy of Sciences · 1989 · 323 citations · Full text

, , +18

Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level.

Gisela K. Haselbacher, J.C. Irminger, J Zapf et al. · Proceedings of the National Academy of Sciences · 1987 · 193 citations · Full text

, , +18

Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?

J. Zapf, E. Futo, M Peter et al. · Journal of Clinical Investigation · 1992 · 173 citations · Full text

, , +16

Clinical studies of IGFBP-2 by radioimmunoassay.

W. F. Blum, Nanette Horn, Jüergen Kratzsch et al. · PubMed · 1993 · 140 citations

, , +17