Familial Mediterranean fever among patients from Karabakh and the diagnostic value of <i>MEFV</i> gene analysis in all classically affected populations

Abstract

These data illuminate the meaning of negative results of MEFV analyses and show that in all populations evaluated, most patients with the NI/NI genotype had disease that mimicked FMF and was unrelated to the MEFV gene. Our findings also demonstrate the high sensitivity of a search for very few mutations in order to perform a molecular diagnosis of MEFV-related FMF.