THE HIGHLY STEREOSELECTIVE SYNTHESIS OF ALL-<i>TRANS</i> AND 13-<i>CIS</i> VITAMIN A VIA DOUBLE ELIMINATION REACTION

Abstract

Abstract Stereocontrolled convergent synthesis of vitamin A was achieved by the double elimination method employing the C10 sulfone and the C10 aldehydes as starting materials. Thus the all-trans and 13-cis isomers were obtained with the stereochemical purity of 95% and 90%, respectively.