Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Bertram Pitt, Faı̈ez Zannad, Willem J. Remme et al. · New England Journal of Medicine · 1999 · 9.1K citations · Full text

Medicine, Cardiology, Pharmacology +16

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Bertram Pitt, Faı̈ez Zannad, Willem J. Remme et al. · Survey of Anesthesiology · 2000 · 2.9K citations

Medicine, Cardiology, Pharmacology +16

Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group.

Karl Swedberg, P. Eneroth, John Kjekshus et al. · Circulation · 1990 · 1.2K citations · Full text

Medicine, Cardiology, Pharmacology +13

Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure

Faı̈ez Zannad, François Alla, A.J. Pérez Pérez et al. · Circulation · 2000 · 943 citations · Full text

Medicine, Cardiology, Physiology +16

Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease

Christopher P. Appleton, James M. Galloway, Mark S. Gonzalez et al. · Journal of the American College of Cardiology · 1993 · 778 citations

Medicine, Cardiology, Internal Medicine +16