Mechanism of Action of Inhalational Anesthesia on Airways

Abstract

To separate reflex from direct actions of anesthetics on airways, we studied the effects of halothane and isoflurane (1.5 MAC) on Ascaris antigen-induced (a mixed reflex and direct stimulus) and methacholine-induced (a direct acting stimulus) airway constriction in Basenji-Greyhound dogs. Prior to a