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RETINAL METABOLISM IN DIABETES: THE METABOLISM OF RETINAE OF NORMAL AND ALLOXAN-DIABETIC RABBITS
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0
References
1951
Year
Ocular DiseaseOptogeneticsOxidative StressDiabetic RetinopathyRetinaGlucose SubstrateHealth SciencesOphthalmologyBiochemistryNormal RabbitsPharmacologyOcular TissueExperimental OphthalmologyPhysiologyDiabetesNormal Rabbit RetinaeGlaucomaMetabolismMedicine
The metabolism of the retinae from alloxan-diabetic rabbits has been compared with that of the retinae of normal rabbits. With glucose substrate, the Q o and Q N 2 G were significantly lower in the alloxan-diabetic than in the normal rabbit retinae. The Q o 2 of the normal rabbit retinae was the same with pyruvate as substrate as with glucose. With the retinae from alloxan-diabetic rabbits, the Q o 2 with pyruvate as substrate was significantly greater than the Q o 2 with glucose as substrate, as well as the Q o 2 of the normal rabbit retinae with pyruvate substrate.