FACTORS ASSOCIATED WITH ASPIRIN RESISTANCE IN PATIENTS PREMEDICATED WITH ASPIRIN AND CLOPIDOGREL FOR ENDOVASCULAR NEUROSURGERY

Abstract

Twenty-one percent of patients premedicated with aspirin and clopidogrel dual therapy for 7 days before endovascular neurosurgical procedures were nonresponders to aspirin. Patients not taking an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker may be at higher risk for aspirin drug resistance.