A Highly Selective Fluorescent Probe for Thiophenols

Abstract

A rapid response to thiophenols is obtained with probe 1 (see scheme), which induces a significant (>50-fold) fluorescence enhancement as a result of cleavage of the electron-withdrawing moiety, thus generating strongly fluorescent molecule 2. No fluorescence is obtained with aliphatic thiols, including cysteine and glutathione, or other nucleophiles. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z702271_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.