Concepedia

Publication | Closed Access

Relationship between oral mucositis and high-dose methotrexate therapy in pediatric acute lymphoblastic leukemia

DOI

38

Citations

0

References

2008

Year

Takayoshi Maiguma, Yasushi Hayashi, Satoshi Ueshima, Hiroaki Kaji, Takashi Egawa, Kazuaki Chayama, Tsuneo Morishima, Yoshihisa Kitamura, Toshihiko Sendo, Yutaka Gomita,
International Journal of Clinical Pharmacology and Therapeutics

Abstract

It seems that there is no significant relationship between the serum MTX concentration and oral mucositis. This in vitro study has demonstrated that the cell injury was related to the duration of MTX exposure rather than a high MTX concentration.